Coinfección entre SARS-COV-2 y dengue en pacientes de Jipijapa de marzo a diciembre del 2020

Authors

Cinthya Verónica Acosta Santana Programa de Maestría en Biomedicina, Instituto de Posgrado, Universidad Técnica de Manabí. Hospital del Día Jipijapa, Instituto Ecuatoriano de Seguridad Social, Jipijapa, Manabí, Ecuador
Minerva Casilda Donate Pino Universidad Técnica de Manabí, Facultad de Ciencias de la Salud, Carrera de Medicina, Portoviejo, Manabí, Ecuador https://orcid.org/0000-0002-5139-4885

DOI:

https://doi.org/10.33936/qkrcs.v7i1.5533

Keywords:

SARS-COV-2, COVID-19, dengue, coinfección, biomarcadores

Abstract

El dengue es la enfermedad arboviral más común en las regiones tropicales y subtropicales del mundo. Al igual que otras regiones, las áreas endémicas de dengue han enfrentado el impacto socioeconómico y de salud pública adicional de la pandemia de la enfermedad por coronavirus 2019 (COVID-19). Las coinfecciones por SARS-CoV-2 y el virus del dengue (DENV) han sido informadas con manejo complicado del paciente y requisitos de atención. El presente estudio tuvo como objetivo, evaluar la coinfección por SARS-CoV-2 y DENV, confirmados a través de técnicas moleculares e inmunológicas, en pacientes atendidos entre marzo y diciembre del 2020, en el Hospital del Día Jipijapa del Instituto Ecuatoriano de Seguridad Social. Se realizó un estudio de tipo transversal, observacional y retrospectivo. La población estuvo constituida por 239 pacientes de entre 10 y 90 años de edad. El muestreo fue no probabilístico. El diagnóstico de COVID-19 se confirmó mediante el ensayo de reacción en cadena de la polimerasa con transcripción inversa (qRT-PCR) de muestras de hisopado nasofaríngeo, mientras que el diagnóstico de dengue se determinó mediante una prueba rápida para NS1Ag/IgG/IgM. El 3,35 % de los pacientes con sintomatología, presentó coinfección, afectando en mayor proporción al sexo masculino. Los principales síntomas se asociaron con malestar general, fiebre, cefalea, dolor abdominal, deposiciones líquidas y tos no productiva. Los resultados de los marcadores hematológicos indicaron leucopenia, leucocitosis y trombocitopenia.

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